During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

The mystery of early embryonic communication is starting to be unraveled thanks to a new stem cell-based model.

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Advances in organoids and embryonic models of human development have the potential to prompt social and existential questions --e.g., what defines human individuality? However, bioethicists say that ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

Scientists have created models of human embryos by programming stem cells. The models give a glimpse into a key stage of development that can reveal new insights into genetic disorders and preventing ...

Technological, ethical and legal issues have limited the understanding of the early stages of embryonic development in humans, despite its importance in basic developmental biology and reproductive ...

The biological and legal definitions of “embryo” don’t match, and that will become a problem, according to Nicolas Rivron, PhD, of the Institute of Molecular Biotechnology of the Austrian Academy of ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...