The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...
Native Read Sequencing for Methylation Profiling in Cancer and Neurodegenerative Disease Diagnostics
Methylation analysis holds significant promise for clinical diagnostics, yet its use has been limited due to challenges posed by legacy technologies that undermine clinical applicability, such as ...
In recent years, the study of epigenetics and its role in disease has increased dramatically. DNA methylation, which influences the ability of proteins to bind the DNA and thereby regulates gene ...
Researchers at the Hebrew University have developed an exceptionally accurate method for predicting chronological age from DNA, based on two short genomic regions. Using deep learning networks ...
LONDON & LOS ANGELES--(BUSINESS WIRE)--DnaNudge, a medical and consumer genetics testing innovator and a spin-out of Imperial College London, today announced that it has signed a multi-million-dollar ...
One of the first signs of bladder cancer can be blood in the urine (hematuria). Investigators developed and analyzed the results of a streamlined and simplified DNA-based urine test to improve the ...
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