If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may also hide a critical, underappreciated source of disease. Scientists are ...

Organisms like eukaryotes and prokaryotes have sophisticated mechanisms of DNA repair after damage. Failure of repairing the DNA damage is considered to be the cause of induction of cell death, ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...