The effect of anti-Lyt2 on the generation of helper T-cell function and on cytotoxic effects specific for subregions of the major histocompatibility complex (MHC) was determined. The addition of ...
Figure 1: The MHC class I and MHC class II antigen-presentation pathways. Here, we discuss the essential role of the NLR family member NLRC5 in the transcriptional regulation of MHC class I genes and ...
Figure 1: MHC class II molecules are ubiquitinated in dendritic cells. Figure 2: Differential localization and endocytosis of wild-type MHC II versus the ubiquitin-deficient MHC IIβ(K>R) mutant.
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