A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will fit into a cell’s nucleus, while the crucial parts of it remain accessible ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...

Researchers from the University of Chicago (IL, USA) have reported that unstable, or ‘noisy’, chromatin enables cells to take on different roles in the body. This flexibility can support the immune ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...