A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

DNA inside human cells is not free-floating. Instead, it is tightly wrapped around small protein units forming a long chain, with DNA looping around each unit before moving on to the next. This ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...