Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Cancer remains a leading health challenge in the U.S., but lifestyle choices — especially diet — can play a role in lowering the risk.

Each year, approximately 36,000 people are diagnosed with the disease in the United States, according to the American Cancer ...

A leading oncologist reveals science-backed foods that may help lower cancer risk, highlighting how a plant-forward, fiber-rich diet can reduce inflammation and support long-term health.

Methionine restriction (MR) has shown significant promise in cancer therapy because it targets the unique methionine dependency of many tumors. However, despite extensive research on MR, a clear ...

PI3K/AKT/mTOR pathway blockade with pan-PI3K/mTORC1/2 inhibition produced substantial PFS gains in PIK3CA wild-type disease, addressing an unmet need after CDK4/6 plus endocrine resistance. Adding ...