Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
The field of cancer research is increasingly exploring the intricate intersections among epigenetics, cancer metabolism, and immunotherapy. These ...
Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...
Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...
Siddhartha Mukherjee, oncologist and author of “The Emperor of All Maladies,” asks: What if we change what a tumor can eat?
Phase 1a/1b study in 97 patients demonstrates mitochondrial metabolic reprogramming induced by BPM31510-IV and supports advancement in multiple ...
Hyeyoung Nam, Ph.D., professor in the UAB Department of Urology, has been published in Science Advances alongside corresponding author, Sunil Sudarshan, M.D. and colleagues Richard L. Kirkman and ...
The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive ...
A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
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