In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

FGF basic is a member of the FGF family, which includes at least 23 related mitogenic proteins sharing 35–60% amino acid conservation. Unlike most other FGFs, FGF acidic and FGF basic lack signal ...

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for ...