Cooperative binding processes are widespread in Nature and are important for regulation of key enzymes and receptors. In general, cooperativity is controlled by an allosteric response to ligand ...

Allosteric ligands interact with binding sites on the receptor molecule that are topographically distinct from the binding site for the endogenous agonist (the orthosteric site). Allosteric modulators ...

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

Researchers at Yale say they used Google to help unravel the complex structure and regulation of enzymes. In a new study, “Eigenvector centrality for characterization of protein allosteric pathways,” ...

Professor Nicolas Doucet and his team at Institut national de la recherche scientifique (INRS) made a major breakthrough earlier this year in the field of evolutionary conservation of molecular ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the Institute of Science Tokyo reveal that a tandem allosteric effect of ...