Randomized clinical trials serve as the standard for clinical research and have contributed immensely to advances in patient care. Nevertheless, several shortcomings of randomized clinical trials have ...

Change is fun. Change is hard. Between those truths, there yawns a large gap that poses a challenge for would-be change makers. Yet by integrating two widely influential practices—design thinking and ...

In recent years, the use of adaptive design methods has become very popular due to its flexibility for identifying clinical benefits of the testing drug. Adaptive designs offer the potential to reduce ...