Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Trained immunity enhances innate immune responses, yet a Western lifestyle may lead to maladaptive trained immunity and drive ...

Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...